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| Author | Topic: Certain on-topic science issues |
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Yul Tolbert (Moderator) |
posted 12/15/04 11:49 PM
Certain on-topic science issues: [This message has been edited on 12/16/2004] |
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Yul Tolbert (Moderator) |
posted 12/15/04 11:51 PM
FROM MARYANN: Aromatherapy, essential oils http://aromatherapy.dostweb.com/ Aromatherapy, essential oils [This message has been edited on 12/16/2004] |
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Yul Tolbert (Moderator) |
posted 12/15/04 11:52 PM
FROM SOMU: Doxorubicin (Adriamycin) Breast cancer resources Breast cancer information Polycythemia vera Medical resources Breast reconstruction surgery Ovarian cancer resources Autos auctions travel news jobs online shopping Breast cancer, Ovarian caner Risk factors for breast cancer Treatment of breast cancer Breast cancer resources Genetic testing in cancer BRCA1 and BRCA2 Acupuncture: History and Theory Introduction to apitherapy Acupuncture, Alexander technique, and Angel therapy http://medicineworld.org/cancer/breast/treatment/doxorubicin.html Doxorubicin (Adriamycin) [This message has been edited on 12/16/2004] [This message has been edited on 12/16/2004] |
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Yul Tolbert (Moderator) |
posted 12/15/04 11:52 PM
FROM SUE: Thrombocytopenia I suffer from thrombocytopenia, which is low platelet count. Last time I was watching Star treck, I had a major bleeding from my nose. So I decided to explore the topic of thrombocytopenia. There are many drugs that can cause thrombocytopenia. Some drugs like anticancer drugs and valproic acid causes dose depended decrease in the number of platelets by myelosuppression and are not included in this list. Drugs may also cause thrombocytopenia by immunological mechanisms and many other mechanisms. Immunological drug induced can be mainly be caused by two mechanisms. The first mechanism is caused by drug depended binding of Fab part of the pathological IgG with the platelets, causing their destruction. The best example is the quinidine group of drugs, and seen with many different types of drugs. Fc portion of the IgG molecule is not involved in the binding of the antibody. In the second type the Fab portion of the pathological IgG binds to platelet factor 4 (PF4) and this is more problamatic. When complexed with heparin or other drugs, the Fc portion of the IgG molecule bind to platelet receptors causing platelet activation which may progress. Since Fc portion of the IgG is engaged in binding to the platelets, they are not available to the Fc receptors of the reticulo-endothelial cells. This is the main reason why severe thrombocytopenia is rare in patients with HIT. A list of drugs that may cause thrombocytopenia or low platelet count is listed on the following site. If you have thrombocytopenia, do not take these drugs. Good luck to you. Thrombocytopenia Sue [This message has been edited on 12/16/2004] |
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Yul Tolbert (Moderator) |
posted 12/15/04 11:53 PM
FROM SOMU: It was breast cancer awareness month during October, I posted the links to fund breast cancer research. Thanks, Somu [This message has been edited on 12/16/2004] [This message has been edited on 12/16/2004] |
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